What are the effects of using synthetic cannabinoids like JWH-018, JWH-073, JWH-250 and others?

 What are the effects of using synthetic cannabinoids like JWH-018, JWH-073, JWH-250 and others?

JWH-018, JWH-073, JWH-250 and other similar chemicals are the primary synthetic cannabinoid receptor agonists responsible for the euphoric and psychoactive effects that imitate marijuana and are among the numerous compounds found in herbal incense and smoke blends.  These synthetic cannabinoids do not contain cannabis but produce effects reported up to 4 times the strength of THC/marijuana.  Users indicate the high comes on slow at first, then with surprising potency.  There have been many reports about the adverse effects including agitation, rapid heart rate, confusion, dizziness and nausea.  In fact, the American Association of Poison Control Centers issued a warning about the dangers of synthetic marijuana products in March 2010.  Long-term effects from these research chemicals are unknown.

 (“Synthetic Cannabinoid Testing (urine & oral fluid)”, p.1, 2010, Redwood Toxicology Laboratory)