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What are the cutoff concentrations for initial and confirmation tests?

(a)As a laboratory, you must use the cutoff concentrations displayed in the following table for initial and confirmation drug tests. All cutoff concentrations are expressed in nanograms per milliliter (ng/mL). The table follows:

Type of Drug or Metabolite Initial Test    Confirmation Test
(1)     Marijuana metabolites

(i) Delta-9-tetrahydrocannabinol-9-caroxylic acid (THC)

50 15
(2) Cocaine metabolites

(Benzoylecgonine)

300 150
(3) Phencyclidine (PCP)  25  25
(4) Amphetamines

(i) Amphetamine

(ii) Methamphetamine

1000

500

500 (Specimen must also contain amphetamine at a concentration of greater than or equal to 200 ng/mL

(5) Opiate metabolites

(i) Codeine

(ii) Morphine

(iii) 6acety1morphine

2000

2000

2000

10

Test for 6-AM in the specimen. Conduct this test only when specimen contains morphine

at a concentration greater than or equal to 2000 ng/mL.

(b) On an initial drug test, you must report a result below the cutoff concentration as negative. If the result is at or above the cutoff concentration, you must conduct a confirmation test.

(c) On a confirmation drug test, you must report a result below the cutoff concentration as negative and a result at or above the cutoff concentration as confirmed positive.

(d) You must report quantitative values for morphine or codeine at 15,000 ng/mL or above.

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